Simulation-based learning (SBL) has revolutionized nursing education worldwide by offering a realistic, safe, and interactive environment where learners can apply theoretical knowledge, practice clinical skills, and develop critical thinking. In the face of evolving healthcare demands, global disparities, and patient safety concerns, integrating simulation into nursing curricula has become imperative. This seminar paper explores the significance, benefits, challenges, and best practices of simulation-based learning in nursing education globally. It highlights its contribution to developing clinical competence and reducing medical errors while aligning with global patient safety goals. The paper concludes with recommendations for policy integration, investment in simulation infrastructure, and faculty training to enhance nursing education quality across regions.