Background: Malignant melanoma is an aggressive skin cancer with a high risk of metastasis and mortality, particularly when diagnosed late. Although less common in people with darker skin, melanoma in sub-Saharan Africa is often characterized by delayed presentation contributing to poor outcomes.

Aim: This study aimed to describe the demographic characteristics, anatomic distribution, and temporal trends of malignant melanoma presentations in a tertiary hospital.

Methods: A retrospective review was conducted for 26 patients diagnosed with malignant melanoma between 2014 and 2023. Data on age, sex, anatomic site, and year of diagnosis were extracted from medical records. Statistical analysis was performed using SPSS version 23. Results were summarized using frequencies and percentages.

Results: A total of 26 patients with malignant melanoma were reviewed. Most patients were aged 55–69 years (42.3%), followed by those aged 40–54 years (34.6%). Only one patient (3.8%) was aged 25–39 years, while patients aged 70 years and above accounted for 19.2% of cases. Females slightly predominated, with 14 cases (53.8%), compared with 12 males (46.2%). Yearly distribution showed variability, with peak presentations in 2021 and 2022, each contributing five cases (19.2%). The lowest numbers were recorded in 2018, 2019, and 2023, with one case (3.8%) each. The most common anatomic site was the foot, accounting for 18 cases (69.2%). Other sites were less frequently affected, including the groin, scalp, and thigh (7.7% each), while the mons pubis and palm accounted for 3.8% each.

Conclusion: Malignant melanoma in this study predominantly affected middle-aged and older adults, showed a slight female predominance, and most commonly involved acral sites, particularly the foot. The observed temporal variability underscores the need for improved early detection and surveillance.