Katsina State, located in the extreme northern part of Nigeria within semi-arid Sahelian belt, characterizes the multifaceted interaction between the three critical environmental resources; water, energy and food (WEF) security and the accomplishment of Sustainable Development Goals (SDGs). The study quantifies resource security within a Water-Energy-Food (WEF) nexus context to assess its direct consequences for significant SDGs in the region. Using a mixed-method approach, secondary data from national databases and conducted primary survey (n=400) across the three ecological zones were synthesized. Results reveal a significant level of WEF insecurity: 51% of households experience water scarcity for five months annually, 87% rely on traditional biomass for cooking and 74% face moderate to severe food insecurity.  A substantial negative correlation (r = -0.74, p<0.01) was recorded between a composite WEF Insecurity Index and a localized SDG Progress Index (SDGs 2, 6, 7, 13). The analysis indicates that the unidirectional, sectoral policies exacerbate trade-offs, such as expanded irrigation increasing groundwater stress without clean energy for pumping. The study concludes that attaining SDGs targets in the state requires paradigm shift to quantify nexus-informed governance. The study proposed a Regional-Specific Nexus Security Index a tool for integrated planning, targeting synergistic interventions such as solar-powered irrigation and regenerative agriculture to pause the cycle of resource dearth and improve sustainable development.