This study explores the application of sports science to optimize training methodologies and enhance performance outcomes in wrestling. Given the sport’s physical and technical demands, wrestling requires a multifaceted approach to training that incorporates strength, agility, endurance, and psychological resilience. Through a comprehensive review of current literature and case studies, this article examines advancements in sports science, including biomechanics, physiological conditioning, mental training, and recovery strategies, and their roles in refining wrestlers’ performance. The study highlights how evidence-based training programs tailored to wrestlers’ specific needs—such as weight class and body type—can lead to improved movement efficiency, reduced injury risk, and sustained competitive success. The findings underscore the potential of sports science to revolutionize wrestling training by offering customized, measurable, and effective methodologies that cater to both elite and developing athletes.