Introduction: Choledocholithiasis is the most common cause of bile duct obstruction, occurring in 10-20% of patients with cholecystolithiasis, 7-14% of patients with cholecystectomy, and 18-33% of patients with acute biliary pancreatitis. Objective: To present a case with a giant multiple choledocholithiasis, with good evolution.

Clinical Table: Female patient of 57 years of age, mixed race, smoker, hypertensive, with a history of vesicular lithiasis that was operated 28 years ago where initially it is treated by videolaparoscopy but in the transoperative it is determined its conversion to conventional cholecystectomy. The same goes to consultation of the area because it begins with pain in the epigastrium, dyspepsia, urine dark urine and sometimes gray stool for which they indicate a study and assess by the services of gastroenterology, general surgery where the surgical intervention is decided. Initially treated by ERCP and subsequently performed a Choledocholithotomy with placement of Kerh probe.

Conclusions: The patient showed a favorable evolution.